Publication: The cerebellar mossy fiber synapse as a model for high-frequency transmission in the mammalian CNS
The cerebellar mossy fiber synapse as a model for high-frequency transmission in the mammalian CNS
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Delvendahl, I., & Hallermann, S. (2016). The cerebellar mossy fiber synapse as a model for high-frequency transmission in the mammalian CNS. Trends in Neurosciences, 39(11), 722–737. https://doi.org/10.1016/j.tins.2016.09.006
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The speed of neuronal information processing depends on neuronal firing frequency. Here, we describe the evolutionary advantages and ubiquitous occurrence of high-frequency firing within the mammalian nervous system in general. The highest firing frequencies so far have been observed at the cerebellar mossy fiber to granule cell synapse. The mechanisms enabling high-frequency transmission at this synapse are reviewed and compared with other synapses. Finally, information coding of high-frequency signals at the mossy fiber synapse is d
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Delvendahl, I., & Hallermann, S. (2016). The cerebellar mossy fiber synapse as a model for high-frequency transmission in the mammalian CNS. Trends in Neurosciences, 39(11), 722–737. https://doi.org/10.1016/j.tins.2016.09.006