Publication: Using azobenzene photocontrol to set proteins in motion
Using azobenzene photocontrol to set proteins in motion
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Bozovic, O., Jankovic, B., & Hamm, P. (2022). Using azobenzene photocontrol to set proteins in motion. Nature Reviews Chemistry, 6(2), 112–124. https://doi.org/10.1038/s41570-021-00338-6
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Controlling the activity of proteins with azobenzene photoswitches is a potent tool for manipulating their biological function. With the help of light, it is possible to change binding affinities, control allostery or manipulate complex biological processes, for example. Additionally, owing to their intrinsically fast photoisomerization, azobenzene photoswitches can serve as triggers that initiate out-of-equilibrium processes. Such switching of the activity initiates a cascade of conformational events that can be accessed with time-re
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Bozovic, O., Jankovic, B., & Hamm, P. (2022). Using azobenzene photocontrol to set proteins in motion. Nature Reviews Chemistry, 6(2), 112–124. https://doi.org/10.1038/s41570-021-00338-6
