Publication: Betaine homocysteine methyl transferase 1, a novel auto-antigen associated with anti-Golgi immune reactivity
Betaine homocysteine methyl transferase 1, a novel auto-antigen associated with anti-Golgi immune reactivity
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Van den Bergh, K., Vercammen, M., Regenass, S., Derua, R., Vermeersch, P., Pokreisz, P., Ocmant, A., de Beéck, K. O., Janssens, S., Waelkens, E., & Bossuyt, X. (2011). Betaine homocysteine methyl transferase 1, a novel auto-antigen associated with anti-Golgi immune reactivity. Clinica Chimica Acta, 413(1–2), 105–108. https://doi.org/10.1016/j.cca.2011.09.001
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Anti-Golgi antibodies are rare autoantibodies that have been described in systemic autoimmune diseases. Not all Golgi auto-antigens are known. The objective of this study was to identify a novel auto-antigen associated with anti-Golgi immune reactivity. Sera from a patient with Golgi immune reactivity and from a control individual were used for Western blotting after 2-dimensional gel separation of a rat Golgi-enriched extract. Betaine homocysteine S-methyltransferase 1 (BHMT1) was identified as an auto-antigen by MALDI-TOF/TOF mass s
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- Van den Bergh, K
- Vercammen, M
- Regenass, S
- Derua, R
- Vermeersch, P
- Pokreisz, P
- Ocmant, A
- de Beéck, K O
- Janssens, S
- Waelkens, E
- Bossuyt, X
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Van den Bergh, K., Vercammen, M., Regenass, S., Derua, R., Vermeersch, P., Pokreisz, P., Ocmant, A., de Beéck, K. O., Janssens, S., Waelkens, E., & Bossuyt, X. (2011). Betaine homocysteine methyl transferase 1, a novel auto-antigen associated with anti-Golgi immune reactivity. Clinica Chimica Acta, 413(1–2), 105–108. https://doi.org/10.1016/j.cca.2011.09.001