Publication:

The photoreceptor cilium and its diseases

Date

Date

Date
2019
Journal Article
Published version

Citations

Citation copied

Bachmann-Gagescu, R., & Neuhauss, S. C. F. (2019). The photoreceptor cilium and its diseases. Current Opinion in Genetics & Development, 56, 22–33. https://doi.org/10.1016/j.gde.2019.05.004

Abstract

Abstract

Abstract

Light sensation occurs in photoreceptor outer segments (OS), which derive from highly specialized primary cilia, based on structural and molecular similarities. Ciliary dysfunction causes ciliopathies, in which retinal degeneration is common. The connecting cilium (CC) is the obligate passage for proteins moving between ciliary and cellular compartment, controlling the correct distribution of proteins on either side of its barrier. While new mechanisms for selective entry of ciliary proteins are being elucidated, active transport out

Additional indexing

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
56

Page range/Item number

Page range/Item number

Page range/Item number
22

Page end

Page end

Page end
33

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Genetics (clinical), Photoreceptors, outer segments, connecting cilium, trafficking, retinal ciliopathies

Language

Language

Language
English

Publication date

Publication date

Publication date
2019-06

Date available

Date available

Date available
2020-01-23

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0959-437X

OA Status

OA Status

OA Status
Hybrid

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Bachmann-Gagescu, R., & Neuhauss, S. C. F. (2019). The photoreceptor cilium and its diseases. Current Opinion in Genetics & Development, 56, 22–33. https://doi.org/10.1016/j.gde.2019.05.004

Hybrid Open Access
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Files
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Files

Files

Files
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