Publication: Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease
Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease
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Buoso, S., Manzoni, A., Alkadhi, H., Plass, A., Quarteroni, A., & Kurtcuoglu, V. (2019). Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease. Biomechanics and Modeling in Mechanobiology, 18(6), 1867–1881. https://doi.org/10.1007/s10237-019-01182-w
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We present a novel computational approach, based on a parametrized reduced-order model, for accelerating the calculation of pressure drop along blood vessels. Vessel lumina are defined by a geometric parametrization using the discrete empirical interpolation method on control points located on the surface of the vessel. Hemodynamics are then computed using a reduced-order representation of the parametrized three-dimensional unsteady Navier-Stokes and continuity equations. The reduced-order model is based on an offline-online splitting
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- Buoso, Stefano
- Manzoni, Andrea
- Alkadhi, Hatem
- Plass, André
- Quarteroni, Alfio
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Buoso, S., Manzoni, A., Alkadhi, H., Plass, A., Quarteroni, A., & Kurtcuoglu, V. (2019). Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease. Biomechanics and Modeling in Mechanobiology, 18(6), 1867–1881. https://doi.org/10.1007/s10237-019-01182-w
