Publication: aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data
aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data
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Citations
Rosenberger, G., Ludwig, C., Röst, H. L., Aebersold, R., & Malmström, L. (2014). aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data. Bioinformatics, 30(17), 2511–2513. https://doi.org/10.1093/bioinformatics/btu200
Abstract
Abstract
Abstract
Motivation: The determination of absolute quantities of proteins in biological samples is necessary for multiple types of scientific inquiry. While relative quantification has been commonly used in proteomics, few proteomic datasets measuring absolute protein quantities have been reported to date. Various technologies have been applied using different types of input data, e.g. ion intensities or spectral counts, as well as different absolute normalization strategies. To date, a user-friendly and transparent software supporting large-s
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Creators (Authors)
- Rosenberger, George
- Ludwig, Christina
- Röst, Hannes L
- Aebersold, Ruedi
- Malmström, Lars
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Citations
Rosenberger, G., Ludwig, C., Röst, H. L., Aebersold, R., & Malmström, L. (2014). aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data. Bioinformatics, 30(17), 2511–2513. https://doi.org/10.1093/bioinformatics/btu200
