Publication: IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens
IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens
Date
Date
Date
Citations
Santourlidis, S., Ghanjati, F., Beermann, A., Hermanns, T., & Poyet, C. (2016). IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens. BioTechniques, 60(2), 84–87. https://doi.org/10.2144/000114379
Abstract
Abstract
Abstract
Sensitive, accurate, and reliable measurements of tumor cell-specific DNA methylation changes are of fundamental importance in cancer diagnosis, prognosis, and monitoring. Real-time methylation-specific PCR (MSP) using intercalating dyes is an established method of choice for this purpose. Here we present a simple but crucial adaptation of this widely applied method that overcomes a major obstacle: genetic abnormalities in the DNA samples, such as aneuploidy or copy number variations, that could result in inaccurate results due to imp
Additional indexing
Creators (Authors)
- Santourlidis, Simeon
- Ghanjati, Foued
- Beermann, Agnes
- Hermanns, Thomas
- Poyet, Cédric
Volume
Volume
Volume
Number
Number
Number
Page Range
Page Range
Page Range
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Citations
Santourlidis, S., Ghanjati, F., Beermann, A., Hermanns, T., & Poyet, C. (2016). IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens. BioTechniques, 60(2), 84–87. https://doi.org/10.2144/000114379
