Publication: Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour
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Frechin, M., Stoeger, T., Daetwyler, S., Gehin, C., Battich, N., Damm, E.-M., Stergiou, L., Riezman, H., & Pelkmans, L. (2015). Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour. Nature, 523(7558), 88–91. https://doi.org/10.1038/nature14429
Abstract
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Abstract
Cells sense the context in which they grow to adapt their phenotype and allow multicellular patterning by mechanisms of autocrine and paracrine signalling. However, patterns also form in cell populations exposed to the same signalling molecules and substratum, which often correlate with specific features of the population context of single cells, such as local cell crowding. Here we reveal a cell-intrinsic molecular mechanism that allows multicellular patterning without requiring specific communication between cells. It acts by sensin
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Creators (Authors)
- Frechin, Mathieu
- Stoeger, Thomas
- Daetwyler, Stephan
- Gehin, Charlotte
- Battich, Nico
- Damm, Eva-Maria
- Stergiou, Lilli
- Riezman, Howard
- Pelkmans, Lucas
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Citations
Frechin, M., Stoeger, T., Daetwyler, S., Gehin, C., Battich, N., Damm, E.-M., Stergiou, L., Riezman, H., & Pelkmans, L. (2015). Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour. Nature, 523(7558), 88–91. https://doi.org/10.1038/nature14429
