Publication: Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation
Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation
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Weber, F. A., Bartolomei, G., Hottiger, M. O., & Cinelli, P. (2013). Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation. Stem Cells, 31(11), 2364–2373. https://doi.org/10.1002/stem.1507
Abstract
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Abstract
The recently established reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka represents a valuable tool for future therapeutic applications. To date, the mechanisms underlying this process are still largely unknown. In particular, the mechanisms how the Yamanaka factors (Oct4, Sox2, Klf4, and c-Myc) directly drive reprogramming and which additional components are involved are still not yet understood. In this study, we aimed at analyzing the role of ADP-ribosyltransferase diphtheria tox
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Creators (Authors)
- Weber, Fabienne A
- Bartolomei, Giody
- Hottiger, Michael O
- Cinelli, Paolo
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Citations
Weber, F. A., Bartolomei, G., Hottiger, M. O., & Cinelli, P. (2013). Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation. Stem Cells, 31(11), 2364–2373. https://doi.org/10.1002/stem.1507
