Publication: Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial
Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial
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Nowak, A., Boesch, L., Andres, E., Battegay, E., Hornemann, T., Schmid, C., Bischoff-Ferrari, H. A., Suter, P. M., & Krayenbuehl, P.-A. (2016). Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial. Medicine, 95(52), e5353. https://doi.org/10.1097/MD.0000000000005353
Abstract
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Abstract
BACKGROUND: Vitamin D deficiency is frequent and has been associated with fatigue in uncontrolled trials. METHODS: This is the first double-blind placebo-controlled clinical trial to investigate the efficacy of per os vitamin D3 (cholecalciferol) in treating fatigue among otherwise healthy persons with low serum 25-hydroxyvitamin D (25(OH)D) levels. We enrolled 120 individuals (mean age 29 ± 6 years, 53% women) presenting with fatigue and vitamin D deficiency (serum 25(OH)D < 20 μg/L). Participants were randomized to a single oral dos
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- Nowak, Albina
- Boesch, Lukas
- Andres, Erik
- Battegay, Edouard
- Hornemann, Thorsten
- Schmid, Christoph
- Bischoff-Ferrari, Heike A
- Suter, Paolo M
- Krayenbuehl, Pierre-Alexandre
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Nowak, A., Boesch, L., Andres, E., Battegay, E., Hornemann, T., Schmid, C., Bischoff-Ferrari, H. A., Suter, P. M., & Krayenbuehl, P.-A. (2016). Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial. Medicine, 95(52), e5353. https://doi.org/10.1097/MD.0000000000005353
