Publication: Screening for Immunodeficiencies in Children With Invasive Pneumococcal Disease: Six-year Experience From a UK Children's Hospital
Screening for Immunodeficiencies in Children With Invasive Pneumococcal Disease: Six-year Experience From a UK Children's Hospital
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Bijker, E. M., Bateman, E. A. L., Trück, J., Patel, S., & Kelly, D. F. (2022). Screening for Immunodeficiencies in Children With Invasive Pneumococcal Disease: Six-year Experience From a UK Children’s Hospital. The Pediatric Infectious Disease Journal, 41(7), 575–578. https://doi.org/10.1097/INF.0000000000003554
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BACKGROUND A previous study showed that investigation of children with invasive pneumococcal disease (IPD) revealed an immunodeficiency in up to 10% of cases. Following this report, we implemented a protocol to investigate children with IPD, to assess the proportion with an immunodeficiency in our setting.
METHODS We retrospectively identified patients who presented with IPD from January 2015 to November 2020 and collected data from medical records. Immunological investigations included complement C3 and C4 levels, classical and alte
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Bijker, E. M., Bateman, E. A. L., Trück, J., Patel, S., & Kelly, D. F. (2022). Screening for Immunodeficiencies in Children With Invasive Pneumococcal Disease: Six-year Experience From a UK Children’s Hospital. The Pediatric Infectious Disease Journal, 41(7), 575–578. https://doi.org/10.1097/INF.0000000000003554