Publication: Sevoflurane abolishes oxygenation impairment in a long-term rat model of acute lung injury
Sevoflurane abolishes oxygenation impairment in a long-term rat model of acute lung injury
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Müller, M. M. (2017). Sevoflurane abolishes oxygenation impairment in a long-term rat model of acute lung injury. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-150667
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BACKGROUND Patients experiencing acute lung injury (ALI) often need mechanical ventilation for which sedation may be required. In such patients, usually the first choice an intravenously administered drug. However, growing evidence suggests that volatile anesthetics such as sevoflurane are a valuable alternative. In this study, we evaluate pulmonary and systemic effects of long-term (24-hour) sedation with sevoflurane compared with propofol in an in vivo animal model of ALI. METHODS Adult male Wistar rats were subjected to ALI by intr
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Müller, M. M. (2017). Sevoflurane abolishes oxygenation impairment in a long-term rat model of acute lung injury. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-150667
