Publication:

Immunology of progressive multifocal leukoencephalopathy

Date

Date

Date
2015
Journal Article
Published version

Citations

Citation copied

Jelcic, I., Jelcic, I., Faigle, W., Sospedra, M., & Martin, R. (2015). Immunology of progressive multifocal leukoencephalopathy. Journal of Neurovirology, 21, 614–622. https://doi.org/10.1007/s13365-014-0294-y

Abstract

Abstract

Abstract

The high prevalence of asymptomatic JC polyomavirus (JCV) infection in the general population indicates coexistence with the human host and efficient immune control in healthy individuals. For unknown reasons, kidney-resident archetypic JCV strains can turn into neurotropic JCV strains which in hereditary or acquired states of immunodeficiency cause opportunistic infection and cytolytic destruction of glial cells or granule cell neurons resulting in progressive multifocal demyelination in the central nervous system (CNS) or cerebellar

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5 since deposited on 2015-06-05
Acq. date: 2025-11-14

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1 since deposited on 2015-06-05
Acq. date: 2025-11-14

Additional indexing

Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
21

Number

Number

Number
6

Page range/Item number

Page range/Item number

Page range/Item number
614

Page end

Page end

Page end
622

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2015-03-05

Date available

Date available

Date available
2015-06-05

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1355-0284

Additional Information

Additional Information

Additional Information
The final publication is available at Springer via http://dx.doi.org/10.1007/s13365-014-0294-y

OA Status

OA Status

OA Status
Green

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

5 since deposited on 2015-06-05
Acq. date: 2025-11-14

Views

1 since deposited on 2015-06-05
Acq. date: 2025-11-14

Citations

Citation copied

Jelcic, I., Jelcic, I., Faigle, W., Sospedra, M., & Martin, R. (2015). Immunology of progressive multifocal leukoencephalopathy. Journal of Neurovirology, 21, 614–622. https://doi.org/10.1007/s13365-014-0294-y

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