Publication: Fertilization and early embryology: the chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection
Fertilization and early embryology: the chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection
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Macas, E., Imthurn, B., Rosselli, M., & Keller, P. J. (1996). Fertilization and early embryology: the chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection. Human Reproduction, 11(11), 2496–2501. https://doi.org/10.1093/oxfordjournals.humrep.a019147
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Implementation of intracytoplasmic sperm injection (ICSI) in human in-vitro fertilization (IVF) has highlighted the need for information about the risk of nuclear spindle damage caused by this procedure. For this purpose we studied the final products of oocyte meiosis at the first cleavage division of multipronuclear zygotes arising after ICSI, and compared the results with abnormally fertilized oocytes after conventional in-vitro insemination. Of 37 successfully analysed tripronuclear zygotes, 18 had three individual metaphases. Abno
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Macas, E., Imthurn, B., Rosselli, M., & Keller, P. J. (1996). Fertilization and early embryology: the chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection. Human Reproduction, 11(11), 2496–2501. https://doi.org/10.1093/oxfordjournals.humrep.a019147