Publication: Mechano-chemical simulation of solid tumor dynamics for therapy outcome predictions
Mechano-chemical simulation of solid tumor dynamics for therapy outcome predictions
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Hirsch, S., Szczerba, D., Lloyd, B., Bajka, M., Kuster, N., & Székely, G. (2011). Mechano-chemical simulation of solid tumor dynamics for therapy outcome predictions. International Journal of Multiscale Computing and Engineering, 9(2), 231–241. https://doi.org/10.1615/IntJMultCompEng.v9.i2.70
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Abstract
Experimental investigations of tumors often result in data reflecting very complex underlying mechanisms. Computer models of such phenomena enable their analysis and may lead to novel and more efficient therapy strategies. We present a generalized finite-element mechano-chemical model of a solid tumor and assess its suitability for predicting therapy outcome. The model includes hosting tissue, tumor cells (vital and necrotic), nutrient (oxygen), blood vessels, and a growth inhibitor. At a certain time instant of the tumor development
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Hirsch, S., Szczerba, D., Lloyd, B., Bajka, M., Kuster, N., & Székely, G. (2011). Mechano-chemical simulation of solid tumor dynamics for therapy outcome predictions. International Journal of Multiscale Computing and Engineering, 9(2), 231–241. https://doi.org/10.1615/IntJMultCompEng.v9.i2.70