Publication: Alpha-lipoic acid as a new treatment option for Alzheimer's disease - a 48 months follow-up analysis
Alpha-lipoic acid as a new treatment option for Alzheimer's disease - a 48 months follow-up analysis
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Hager, K., Kenklies, M., McAfoose, J., Engel, J., & Münch, G. (2007). Alpha-lipoic acid as a new treatment option for Alzheimer’s disease - a 48 months follow-up analysis. Journal of Neural Transmission. Supplementa, 72, 189–193. https://doi.org/10.1007/978-3-211-73574-9_24
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Oxidative stress and neuronal energy depletion are characteristic biochemical hallmarks of Alzheimer's disease (AD). It is therefore conceivable that pro-energetic and antioxidant drugs such as alpha-lipoic acid might delay the onset or slow down the progression of the disease. In a previous study, 600mg alpha-lipoic acid was given daily to nine patients with AD (receiving a standard treatment with choline-esterase inhibitors) in an open-label study over an observation period of 12 months. The treatment led to a stabilization of cogni
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- McAfoose, J
- Engel, J
- Münch, G
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Hager, K., Kenklies, M., McAfoose, J., Engel, J., & Münch, G. (2007). Alpha-lipoic acid as a new treatment option for Alzheimer’s disease - a 48 months follow-up analysis. Journal of Neural Transmission. Supplementa, 72, 189–193. https://doi.org/10.1007/978-3-211-73574-9_24