Publication: In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity
In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity
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Ludewig, B., Barchiesi, F., Pericin, M., Zinkernagel, R. M., Hengartner, H., & Schwendener, R. (2000). In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity. Vaccine, 19, 23–32. https://doi.org/10.1016/S0264-410X(00)00163-8
Abstract
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Initiation of antiviral and anti-tumour T cell responses is probably achieved mainly by dendritic cells (DC) transporting antigen from the periphery into organised lymphoid tissues. To develop T cell vaccines it is, therefore, important to understand the accessibility of the antigen to DC in vivo and whether DC are activated by vaccination. Here we have evaluated the immunogenicity of a liposomal vaccine formulation with antigenic peptides derived from the glycoprotein of the lymphocytic choriomeningitis virus. Liposome-encapsulated p
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- Ludewig, B
- Barchiesi, F
- Pericin, M
- Zinkernagel, R M
- Hengartner, H
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Citations
Ludewig, B., Barchiesi, F., Pericin, M., Zinkernagel, R. M., Hengartner, H., & Schwendener, R. (2000). In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity. Vaccine, 19, 23–32. https://doi.org/10.1016/S0264-410X(00)00163-8
