Publication: Influence of fiber diameter and surface roughness of electrospun vascular grafts on blood activation
Influence of fiber diameter and surface roughness of electrospun vascular grafts on blood activation
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Milleret, V., Hefti, T., Hall, H., Vogel, V., & Eberli, D. (2012). Influence of fiber diameter and surface roughness of electrospun vascular grafts on blood activation. Acta Biomaterialia, 8(12), 4349–4356. https://doi.org/10.1016/j.actbio.2012.07.032
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Electrospun grafts are widely investigated for vascular graft replacement due to their ease and compatibility with many natural and synthetic polymers. Here, the effect of the processing parameters on the scaffold's architecture and subsequent reactions of partially heparinized blood triggered by contacting these topographies were studied. Degrapol(®) (DP) and poly(lactic-co-glycolic acid (PLGA) electrospun fibrous scaffolds were characterized with regard to fiber diameter, pore area and scaffold roughness. The study showed that elect
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Milleret, V., Hefti, T., Hall, H., Vogel, V., & Eberli, D. (2012). Influence of fiber diameter and surface roughness of electrospun vascular grafts on blood activation. Acta Biomaterialia, 8(12), 4349–4356. https://doi.org/10.1016/j.actbio.2012.07.032