Impact of aerobic fitness on cerebral blood flow and cerebral vascular responsiveness to CO2 in young and older men

Braz, I D; Flück, D; Lip, G Y H; Lundby, C; Fisher, J P

doi:10.1111/sms.12674

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Braz, I. D., Flück, D., Lip, G. Y. H., Lundby, C., & Fisher, J. P. (2017). Impact of aerobic fitness on cerebral blood flow and cerebral vascular responsiveness to CO2 in young and older men. Scandinavian Journal of Medicine & Science in Sports, 27(6), 634–642. https://doi.org/10.1111/sms.12674

Abstract

We sought to test the hypothesis that brain blood flow and cerebral vascular responsiveness to carbon dioxide (CVRCO2 ) are greater in aerobically trained young and old individuals compared to their untrained counterparts. In 11 young trained {[23 (20-26) years] [mean (95% confidence interval)]}, 10 young untrained [25 (22-28) years], 8 older trained [65 (61-69) years], and 9 older untrained [67 (64-71) years] healthy individuals, Doppler ultrasound of the internal carotid (ICA) and vertebral (VA) artery blood flow were determined, al