Publication: Single-molecule electrometry
Single-molecule electrometry
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Ruggeri, F., Zosel, F., Mutter, N., Różycka, M., Wojtas, M., Ożyhar, A., Schuler, B., & Krishnan, M. (2017). Single-molecule electrometry. Nature Nanotechnology, 12, 488–495. https://doi.org/10.1038/nnano.2017.26
Abstract
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Abstract
Mass and electrical charge are fundamental properties of biological macromolecules. Although molecular mass has long been determined with atomic precision, a direct and precise determination of molecular charge remains an outstanding challenge. Here we report high-precision (<1e) measurements of the electrical charge of molecules such as nucleic acids, and globular and disordered proteins in solution. The measurement is based on parallel external field-free trapping of single macromolecules, permits the estimation of a dielectric coef
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Creators (Authors)
- Ruggeri, Francesca
- Zosel, Franziska
- Mutter, Natalie
- Różycka, Mirosława
- Wojtas, Magdalena
- Ożyhar, Andrzej
- Schuler, Benjamin
- Krishnan, Madhavi
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Citations
Ruggeri, F., Zosel, F., Mutter, N., Różycka, M., Wojtas, M., Ożyhar, A., Schuler, B., & Krishnan, M. (2017). Single-molecule electrometry. Nature Nanotechnology, 12, 488–495. https://doi.org/10.1038/nnano.2017.26
