Publication: Influence of cortisol cosecretion on non-ACTH-stimulated adrenal venous sampling in primary aldosteronism: a retrospective cohort study
Influence of cortisol cosecretion on non-ACTH-stimulated adrenal venous sampling in primary aldosteronism: a retrospective cohort study
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Heinrich, D. A., Quinkler, M., Adolf, C., Handgriff, L., Müller, L., Schneider, H., Sturm, L., Künzel, H., Seidensticker, M., Deniz, S., Ladurner, R., Beuschlein, F., & Reincke, M. (2022). Influence of cortisol cosecretion on non-ACTH-stimulated adrenal venous sampling in primary aldosteronism: a retrospective cohort study. European Journal of Endocrinology, 187(5), 637–650. https://doi.org/10.1530/EJE-21-0541
Abstract
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OBJECTIVE
Cortisol measurements are essential for the interpretation of adrenal venous samplings (AVS) in primary aldosteronism (PA). Cortisol cosecretion may influence AVS indices. We aimed to investigate whether cortisol cosecretion affects non-adrenocorticotrophic hormone (ACTH)-stimulated AVS results.
DESIGN
Retrospective cohort study at a tertiary referral center.
METHODS
We analyzed 278 PA patients who underwent non-ACTH-stimulated AVS and had undergone at least a 1-mg dexamethasone suppression test (DST). Subsets underwent
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Heinrich, D. A., Quinkler, M., Adolf, C., Handgriff, L., Müller, L., Schneider, H., Sturm, L., Künzel, H., Seidensticker, M., Deniz, S., Ladurner, R., Beuschlein, F., & Reincke, M. (2022). Influence of cortisol cosecretion on non-ACTH-stimulated adrenal venous sampling in primary aldosteronism: a retrospective cohort study. European Journal of Endocrinology, 187(5), 637–650. https://doi.org/10.1530/EJE-21-0541