Publication: Erythropoietin stimulates GABAergic maturation in the mouse hippocampus
Erythropoietin stimulates GABAergic maturation in the mouse hippocampus
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Citations
Khalid, K., Frei, J., Aboouf, M. A., Koester-Hegmann, C., Gassmann, M., Fritschy, J.-M., & Schneider Gasser, E. M. (2021). Erythropoietin stimulates GABAergic maturation in the mouse hippocampus. ENeuro, 8(1), 1–20. https://doi.org/10.1523/ENEURO.0006-21.2021
Abstract
Abstract
Abstract
Several neurodevelopmental disabilities are strongly associated with alterations in GABAergic transmission, and therapies to stimulate its normal development are lacking. Erythropoietin (EPO) is clinically used in neonatology to mitigate acute brain injury, and to stimulate neuronal maturation. Yet it remains unclear whether EPO can stimulate maturation of the GABAergic system. Here, with the use of a transgenic mouse line that constitutively overexpresses neuronal EPO (Tg21), we show that EPO stimulates postnatal GABAergic maturation
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Creators (Authors)
- Khalid, Kasifa
- Frei, Julia
- Aboouf, Mostafa A
- Koester-Hegmann, Christina
- Gassmann, Max
- Fritschy, Jean-Marc
- Schneider Gasser, Edith M
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Citations
Khalid, K., Frei, J., Aboouf, M. A., Koester-Hegmann, C., Gassmann, M., Fritschy, J.-M., & Schneider Gasser, E. M. (2021). Erythropoietin stimulates GABAergic maturation in the mouse hippocampus. ENeuro, 8(1), 1–20. https://doi.org/10.1523/ENEURO.0006-21.2021
