Publication: Selective condensation drives partitioning and sequential secretion of cyst wall proteins in differentiating giardia lamblia
Selective condensation drives partitioning and sequential secretion of cyst wall proteins in differentiating giardia lamblia
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Konrad, C., Spycher, C., & Hehl, A. B. (2010). Selective condensation drives partitioning and sequential secretion of cyst wall proteins in differentiating giardia lamblia. PLoS Pathogens, 6(4), e1000835. https://doi.org/10.1371/journal.ppat.1000835
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Controlled secretion of a protective extracellular matrix is required for transmission of the infective stage of a large number of protozoan and metazoan parasites. Differentiating trophozoites of the highly minimized protozoan parasite Giardia lamblia secrete the proteinaceous portion of the cyst wall material (CWM) consisting of three paralogous cyst wall proteins (CWP1–3) via organelles termed encystation-specific vesicles (ESVs). Phylogenetic and molecular data indicate that Diplomonads have lost a classical Golgi during reductive
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Konrad, C., Spycher, C., & Hehl, A. B. (2010). Selective condensation drives partitioning and sequential secretion of cyst wall proteins in differentiating giardia lamblia. PLoS Pathogens, 6(4), e1000835. https://doi.org/10.1371/journal.ppat.1000835