Publication: Nitrite stress increases staphylococcal enterotoxin C transcription and triggers the SigB regulon
Nitrite stress increases staphylococcal enterotoxin C transcription and triggers the SigB regulon
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Etter, D., Büchel, R., Patt, T., Biggel, M., Tasara, T., Cernela, N., Stevens, M. J. A., & Johler, S. (2022). Nitrite stress increases staphylococcal enterotoxin C transcription and triggers the SigB regulon. FEMS Microbiology Letters, 369(1), fnac059. https://doi.org/10.1093/femsle/fnac059
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Staphylococcal food poisoning is a common food intoxication caused by staphylococcal enterotoxins. While growth of Staphylococcus aureus is not inhibited by the meat-curing agent nitrite, we hypothesize that nitrite has an influence on enterotoxin C (SEC) expression. We investigated the influence of 150 mg/l nitrite on SEC expression at mRNA and protein level in seven strains expressing different SEC variants. Additionally, regulatory knockout mutants (Δagr, ΔsarA, and ΔsigB) of high SEC producing strain SAI48 were investigated at mRN
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Etter, D., Büchel, R., Patt, T., Biggel, M., Tasara, T., Cernela, N., Stevens, M. J. A., & Johler, S. (2022). Nitrite stress increases staphylococcal enterotoxin C transcription and triggers the SigB regulon. FEMS Microbiology Letters, 369(1), fnac059. https://doi.org/10.1093/femsle/fnac059