Publication: The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity
The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity
Date
Date
Date
Citations
Rausch, M., Samodelov, S. L., Visentin, M., & Kullak-Ublick, G. A. (2022). The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity. International Journal of Molecular Sciences, 23(22), 13967. https://doi.org/10.3390/ijms232213967
Abstract
Abstract
Abstract
The nuclear receptor farnesoid X receptor (FXR, NR1H4) is a bile acid (BA) sensor that links the enterohepatic circuit that regulates BA metabolism and elimination to systemic lipid homeostasis. Furthermore, FXR represents a real guardian of the hepatic function, preserving, in a multifactorial fashion, the integrity and function of hepatocytes from chronic and acute insults. This review summarizes how FXR modulates the expression of pathway-specific as well as polyspecific transporters and enzymes, thereby acting at the interface of
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Rausch, Magdalena
- Samodelov, Sophia L
- Visentin, Michele
- Kullak-Ublick, Gerd A
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Rausch, M., Samodelov, S. L., Visentin, M., & Kullak-Ublick, G. A. (2022). The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity. International Journal of Molecular Sciences, 23(22), 13967. https://doi.org/10.3390/ijms232213967
