Publication: Grape ASR-Silencing Sways Nuclear Proteome, Histone Marks and Interplay of Intrinsically Disordered Proteins
Grape ASR-Silencing Sways Nuclear Proteome, Histone Marks and Interplay of Intrinsically Disordered Proteins
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Atanassov, H., Parrilla, J., Artault, C., Verbeke, J., Schneider, T., Grossmann, J., Roschitzki, B., & Atanassova, R. (2022). Grape ASR-Silencing Sways Nuclear Proteome, Histone Marks and Interplay of Intrinsically Disordered Proteins. International Journal of Molecular Sciences, 23, 1537. https://doi.org/10.3390/ijms23031537
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In order to unravel the functions of ASR (Abscisic acid, Stress, Ripening-induced) proteins in the nucleus, we created a new model of genetically transformed grape embryogenic cells by RNAi-knockdown of grape ASR (VvMSA). Nuclear proteomes of wild-type and VvMSA-RNAi grape cell lines were analyzed by quantitative isobaric tagging (iTRAQ 8-plex). The most significantly up- or down-regulated nuclear proteins were involved in epigenetic regulation, DNA replication/repair, transcription, mRNA splicing/stability/editing, rRNA processing/bi
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Atanassov, H., Parrilla, J., Artault, C., Verbeke, J., Schneider, T., Grossmann, J., Roschitzki, B., & Atanassova, R. (2022). Grape ASR-Silencing Sways Nuclear Proteome, Histone Marks and Interplay of Intrinsically Disordered Proteins. International Journal of Molecular Sciences, 23, 1537. https://doi.org/10.3390/ijms23031537