Publication: Differential modulation of emotion processing brain regions by noradrenergic and serotonergic antidepressants
Differential modulation of emotion processing brain regions by noradrenergic and serotonergic antidepressants
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Brühl, A. B., Jäncke, L., & Herwig, U. (2011). Differential modulation of emotion processing brain regions by noradrenergic and serotonergic antidepressants. Psychopharmacology, 216(3), 389–399. https://doi.org/10.1007/s00213-011-2227-2
Abstract
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The brain regions involved in the processing of negative emotional stimuli were differentially modulated by selective noradrenergic and serotonergic drugs: thalamic activity was increased by reboxetine, whereas citalopram primarily affected ventrolateral prefrontal regions. Thus, dysfunction in these regions, which could be identified in depressed patients, may predict treatment responses to either noradrenergic or serotonergic antidepressants.
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- Jäncke, Lutz
- Herwig, Uwe
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Brühl, A. B., Jäncke, L., & Herwig, U. (2011). Differential modulation of emotion processing brain regions by noradrenergic and serotonergic antidepressants. Psychopharmacology, 216(3), 389–399. https://doi.org/10.1007/s00213-011-2227-2
