Publication: Establishing a pre-clinical growing animal model to test a tissue engineered valved pulmonary conduit
Establishing a pre-clinical growing animal model to test a tissue engineered valved pulmonary conduit
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Knirsch, W., Krüger, B., Fleischmann, T., Malbon, A., Lipiski, M., Lemme, F., Sauer, M., Cesarovic, N., Dave, H., Hübler, M., & Schweiger, M. (2020). Establishing a pre-clinical growing animal model to test a tissue engineered valved pulmonary conduit. Journal of Thoracic Disease, 12, 1070–1078. https://doi.org/10.21037/jtd.2019.12.70
Abstract
Abstract
Abstract
Background: Many valvular pathologies of the heart may be only sufficiently treated by replacement of the valve if a reconstruction is not feasible. However, structural deterioration, thrombosis with thromboembolic events and infective endocarditis are commonly encountered complications over time and often demand a re-operation. In congenital heart disease the lack of small diameter valves with the potential to grow poses additional challenges and limits treatment options to homo- or xenograft implants. Methods: In this study, a chron
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Creators (Authors)
- Krüger, Bernard
- Fleischmann, Thea
- Malbon, Alexandra
- Lipiski, Miriam
- Lemme, Frithjof
- Sauer, Mareike
- Cesarovic, Niko
- Dave, Hitendu
- Hübler, Michael
- Schweiger, Martin
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Citations
Knirsch, W., Krüger, B., Fleischmann, T., Malbon, A., Lipiski, M., Lemme, F., Sauer, M., Cesarovic, N., Dave, H., Hübler, M., & Schweiger, M. (2020). Establishing a pre-clinical growing animal model to test a tissue engineered valved pulmonary conduit. Journal of Thoracic Disease, 12, 1070–1078. https://doi.org/10.21037/jtd.2019.12.70
