Publication: Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma
Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma
Date
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Citations
Boro, A., Arlt, M. J., Lengnick, H., Robl, B., Husmann, M., Bertz, J., Born, W., & Fuchs, B. (2015). Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma. American Journal of Translational Research, 7(3), 640–653.
Abstract
Abstract
Abstract
Neoadjuvant chemotherapy in osteosarcoma increased the long-term survival of patients with localized disease considerably but metastasizing osteosarcoma remained largely treatment resistant. Neuropilins, transmembrane glycoproteins, are important receptors for VEGF dependent hyper-vascularization in tumor angiogenesis and their aberrant expression promotes tumorigenesis and metastasis in many solid tumors. Our analysis of Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2) immunostaining in a tissue microarray of 66 osteosarcoma patients iden
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Creators (Authors)
- Boro, Aleksandar
- Lengnick, Harald
- Robl, Bernhard
- Husmann, Maren
- Bertz, Josefine
- Born, Walter
- Fuchs, Bruno
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Citations
Boro, A., Arlt, M. J., Lengnick, H., Robl, B., Husmann, M., Bertz, J., Born, W., & Fuchs, B. (2015). Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma. American Journal of Translational Research, 7(3), 640–653.
