Publication: Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
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Helmuth, J. A., Paul, G., & Sbalzarini, I. F. (2010). Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images. BMC Bioinformatics, 11(1), 372. https://doi.org/10.1186/1471-2105-11-372
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Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on spatial proximity, other interactions typically result in spatial correlations between the interacting structures. Such correlations are the target of microscopy-based co-localization analysis, which can provide hints of potential interactions. Two complementary approaches to co-localization analysis can be distinguished: intensity correlation methods capitali
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Helmuth, J. A., Paul, G., & Sbalzarini, I. F. (2010). Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images. BMC Bioinformatics, 11(1), 372. https://doi.org/10.1186/1471-2105-11-372