Publication: The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses
The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses
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Citations
Egholm, C., Heeb, L. E. M., Impellizzieri, D., & Boyman, O. (2019). The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses. Frontiers in Immunology, 10, 2507. https://doi.org/10.3389/fimmu.2019.02507
Abstract
Abstract
Abstract
Interleukin-4 (IL-4) receptor (IL-4R) signaling plays a pivotal role in type 2 immune responses. Type 2 immunity ensures several host-protective processes such as defense against helminth parasites and wound repair, however, type 2 immune responses also drive the pathogenesis of allergic diseases. Neutrophil granulocytes (neutrophils) have not traditionally been considered a part of type 2 immunity. While neutrophils might be beneficial in initiating a type 2 immune response, their involvement and activation is rather unwanted at late
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Creators (Authors)
- Egholm, Cecilie
- Heeb, Lukas E M
- Impellizzieri, Daniela
- Boyman, Onur
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Citations
Egholm, C., Heeb, L. E. M., Impellizzieri, D., & Boyman, O. (2019). The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses. Frontiers in Immunology, 10, 2507. https://doi.org/10.3389/fimmu.2019.02507
