Publication: Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage
Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage
Date
Date
Date
Citations
Muroi, C., Fujioka, M., Mishima, K., Irie, K., Fujimura, Y., Nakano, T., Fandino, J., Keller, E., Iwasaki, K., & Fujiwara, M. (2014). Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage. Journal of Thrombosis and Haemostasis, 12(4), 505–514. https://doi.org/10.1111/jth.12511
Abstract
Abstract
Abstract
Background: Microthrombosis and reactive inflammation contribute to neuronal injury after sub- arachnoid hemorrhage (SAH). ADAMTS-13 cleaves von Willebrand factor multimers, and inhibits thrombus formation and, seemingly, inflammatory reactions. Objective: To investigate the effect of ADAMTS-13 in experi- mental SAH. Methods: A total of 100 male C57/BL6 mice were randomly assigned to four groups: sham (n = 15), SAH (n = 27), vehicle (n = 25), and ADAMTS-13 (n = 23; 100 lL per 10 g of body weight of 100 lg of ADAMTS-13 per 1 mL of 0.9%
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Muroi, C
- Fujioka, M
- Mishima, K
- Irie, K
- Fujimura, Y
- Nakano, T
- Keller, E
- Iwasaki, K
- Fujiwara, M
Volume
Volume
Volume
Number
Number
Number
Page Range
Page Range
Page Range
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
Additional Information
Additional Information
Additional Information
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Muroi, C., Fujioka, M., Mishima, K., Irie, K., Fujimura, Y., Nakano, T., Fandino, J., Keller, E., Iwasaki, K., & Fujiwara, M. (2014). Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage. Journal of Thrombosis and Haemostasis, 12(4), 505–514. https://doi.org/10.1111/jth.12511
