Publication: Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity
Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity
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Thomas, C. W., Guillaumin, M. C. C., McKillop, L. E., Achermann, P., & Vyazovskiy, V. V. (2020). Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity. ELife, 9, e54148. https://doi.org/10.7554/elife.54148
Abstract
Abstract
Abstract
Sleep homeostasis manifests as a relative constancy of its daily amount and intensity. Theoretical descriptions define ‘Process S’, a variable with dynamics dependent on global sleep-wake history, and reflected in electroencephalogram (EEG) slow wave activity (SWA, 0.5–4 Hz) during sleep. The notion of sleep as a local, activity-dependent process suggests that activity history must be integrated to determine the dynamics of global Process S. Here, we developed novel mathematical models of Process S based on cortical activity recorded
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- Thomas, Christopher W
- Guillaumin, Mathilde C C
- McKillop, Laura E
- Vyazovskiy, Vladyslav V
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Citations
Thomas, C. W., Guillaumin, M. C. C., McKillop, L. E., Achermann, P., & Vyazovskiy, V. V. (2020). Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity. ELife, 9, e54148. https://doi.org/10.7554/elife.54148
