Publication: PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids
PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids
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Vallmajo‐Martin, Q., Broguiere, N., Millan, C., Zenobi-Wong, M., & Ehrbar, M. (2020). PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids. Advanced Functional Materials, 30(48), 1910282. https://doi.org/10.1002/adfm.201910282
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Bone marrow (BM) organoids provide powerful tools to study the vital interplay between the BM microenvironment and resident cells. Current biomaterials, however, are limited in terms of versatility for independently studying the biochemical and biophysical properties that regulate BM function. Here, a transglutaminase (TG) crosslinked system that seam-lessly incorporates poly(ethylene glycol) (PEG) and hyaluronic acid (HA) into hybrid hydrogels for the formation of BM analogues is presented. By combining features of PEG and HA, these
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Vallmajo‐Martin, Q., Broguiere, N., Millan, C., Zenobi-Wong, M., & Ehrbar, M. (2020). PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids. Advanced Functional Materials, 30(48), 1910282. https://doi.org/10.1002/adfm.201910282