Publication: Characterization of carbon-coated magnetic nanoparticles using clinical blood coagulation assays: Effect of PEG-functionalization and comparison to silica nanoparticles
Characterization of carbon-coated magnetic nanoparticles using clinical blood coagulation assays: Effect of PEG-functionalization and comparison to silica nanoparticles
Date
Date
Date
Citations
Bircher, L., Theusinger, O. M., Locher, S., Eugster, P., Roth-Z’graggen, B., Schumacher, C. M., Studt, J.-D., Stark, W. J., Beck-Schimmer, B., & Herrmann, I. K. (2014). Characterization of carbon-coated magnetic nanoparticles using clinical blood coagulation assays: Effect of PEG-functionalization and comparison to silica nanoparticles. Journal of Materials Chemistry B, 2, 3753–3758. https://doi.org/10.1039/c4tb00208c
Abstract
Abstract
Abstract
Intravascular application of magnetic nanocarriers is a critical step in the development of new therapeutic strategies, including magnetic drug targeting or hyperthermia. However, injection of particulate matter bears the intrinsic risk of contact activation of the blood coagulation cascade. In this work, we use point-of-care assays to study coagulation dynamics and clotting parameters in blood samples exposed to relevant concentrations of surface-functionalized carbon-coated iron carbide nanomagnets using unmodified nanomagnets and p
Metrics
Views
Additional indexing
Creators (Authors)
- Bircher, Lukas
- Theusinger, Oliver M
- Locher, Silvan
- Eugster, Philipp
- Roth-Z'graggen, Birgit
- Schumacher, Christoph M
- Studt, Jan-Dirk
- Stark, Wendelin J
- Beck-Schimmer, Beatrice
- Herrmann, Inge K
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
Publisher
Publisher
Publisher
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Views
Citations
Bircher, L., Theusinger, O. M., Locher, S., Eugster, P., Roth-Z’graggen, B., Schumacher, C. M., Studt, J.-D., Stark, W. J., Beck-Schimmer, B., & Herrmann, I. K. (2014). Characterization of carbon-coated magnetic nanoparticles using clinical blood coagulation assays: Effect of PEG-functionalization and comparison to silica nanoparticles. Journal of Materials Chemistry B, 2, 3753–3758. https://doi.org/10.1039/c4tb00208c