Publication: Molecular investigations of Rickettsia helvetica infection in dogs, foxes, humans and Ixodes ticks
Molecular investigations of Rickettsia helvetica infection in dogs, foxes, humans and Ixodes ticks
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Boretti, F. S., Perreten, A., Meli, M. L., Cattori, V., Willi, B., Wengi, N., Hornok, S., Honegger, H., Hegglin, D., Woelfel, R., Reusch, C. E., Lutz, H., & Hofmann-Lehmann, R. (2009). Molecular investigations of Rickettsia helvetica infection in dogs, foxes, humans and Ixodes ticks. Applied and Environmental Microbiology, 75(10), 3230–3237. https://doi.org/10.1128/AEM.00220-09
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Rickettsia helvetica, a tick-borne member of the spotted fever group Rickettsiae, is a suspected pathogen in humans; however its role in animals is unknown. The aims of this study were to establish a R. helvetica-specific real-time TaqMan PCR assay and apply it to the analysis of tick vectors (potential exposure risk) and blood samples from Canidae and humans (prevalence of infection). The newly designed 23S rRNA gene assay for R. helvetica was more sensitive than a published citrate synthase (gltA) gene assay for several Rickettsiae.
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Boretti, F. S., Perreten, A., Meli, M. L., Cattori, V., Willi, B., Wengi, N., Hornok, S., Honegger, H., Hegglin, D., Woelfel, R., Reusch, C. E., Lutz, H., & Hofmann-Lehmann, R. (2009). Molecular investigations of Rickettsia helvetica infection in dogs, foxes, humans and Ixodes ticks. Applied and Environmental Microbiology, 75(10), 3230–3237. https://doi.org/10.1128/AEM.00220-09