Publication:

Effect of Cumulating Exposure to Abacavir on the Risk of Cardiovascular Disease Events in Patients From the Swiss HIV Cohort Study

Date

Date

Date
2015
Journal Article
Published version

Citations

Citation copied

Young, J., Xiao, Y., Moodie, E. E. M., Abrahamowicz, M., Klein, M. B., Bernasconi, E., Schmid, P., Calmy, A., Cavassini, M., Cusini, A., Weber, R., & Bucher, H. C. (2015). Effect of Cumulating Exposure to Abacavir on the Risk of Cardiovascular Disease Events in Patients From the Swiss HIV Cohort Study. Journal of Acquired Immune Deficiency Syndromes, 69, 413–421. https://doi.org/10.1097/QAI.0000000000000662

Abstract

Abstract

Abstract

BACKGROUND: Patients with HIV exposed to the antiretroviral drug abacavir may have an increased risk of cardiovascular disease (CVD). There is concern that this association arises because of a channeling bias. Even if exposure is a risk, it is not clear how that risk changes as exposure cumulates. METHODS: We assess the effect of exposure to abacavir on the risk of CVD events in the Swiss HIV Cohort Study. We use a new marginal structural Cox model to estimate the effect of abacavir as a flexible function of past exposures while accou

Metrics

Downloads

6 since deposited on 2015-12-17
Acq. date: 2025-11-12

Views

1 since deposited on 2015-12-17
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

  • Young, Jim
    affiliation.icon.alt
  • Xiao, Yongling
    affiliation.icon.alt
  • Moodie, Erica E M
    affiliation.icon.alt
  • Abrahamowicz, Michal
    affiliation.icon.alt
  • Klein, Marina B
    affiliation.icon.alt
  • Bernasconi, Enos
    affiliation.icon.alt
  • Schmid, Patrick
    affiliation.icon.alt
  • Calmy, Alexandra
    affiliation.icon.alt
  • Cavassini, Matthias
    affiliation.icon.alt
  • Cusini, Alexia
    affiliation.icon.alt
  • Weber, Rainer
    affiliation.icon.alt
  • Bucher, Heiner C
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
69

Number

Number

Number
4

Page range/Item number

Page range/Item number

Page range/Item number
413

Page end

Page end

Page end
421

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2015-08-01

Date available

Date available

Date available
2015-12-17

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1525-4135

OA Status

OA Status

OA Status
Green

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

6 since deposited on 2015-12-17
Acq. date: 2025-11-12

Views

1 since deposited on 2015-12-17
Acq. date: 2025-11-12

Citations

Citation copied

Young, J., Xiao, Y., Moodie, E. E. M., Abrahamowicz, M., Klein, M. B., Bernasconi, E., Schmid, P., Calmy, A., Cavassini, M., Cusini, A., Weber, R., & Bucher, H. C. (2015). Effect of Cumulating Exposure to Abacavir on the Risk of Cardiovascular Disease Events in Patients From the Swiss HIV Cohort Study. Journal of Acquired Immune Deficiency Syndromes, 69, 413–421. https://doi.org/10.1097/QAI.0000000000000662

Green Open Access
Loading...
Thumbnail Image

Files

Files

Files
Files available to download:1

Files

Files

Files
Files available to download:1
Loading...
Thumbnail Image