Publication: Identification of Colonization Factors in $\textit{Burkholderia}$ by Applying Genome-Wide Mutant Profiling
Identification of Colonization Factors in $\textit{Burkholderia}$ by Applying Genome-Wide Mutant Profiling
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Paszti, S. (2025). Identification of Colonization Factors in $\textit{Burkholderia}$ by Applying Genome-Wide Mutant Profiling. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-270799
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In the 1980s, the first members of the Burkholderia cepacia complex (Bcc), which were previously known only as pathogens of onions, were isolated from cystic fibrosis (CF) patients. Infections with members of the Bcc are difficult to treat and are associated with high mortality rates in CF patients. Bcc infections are often severe and can cause the “cepacia syndrome”, a necrotizing pneumonia that results in the rapid decline of lung function. Treatment with antibiotics usually fails to eradicate Bcc infections due to their high metabo
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Paszti, S. (2025). Identification of Colonization Factors in $\textit{Burkholderia}$ by Applying Genome-Wide Mutant Profiling. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-270799
