Publication: Knockdown of Drosophila hemoglobin suggests a role in O2 homeostasis
Knockdown of Drosophila hemoglobin suggests a role in O2 homeostasis
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Gleixner, E., Ripp, F., Gorr, T. A., Schuh, R., Wolf, C., Burmester, T., & Hankeln, T. (2016). Knockdown of Drosophila hemoglobin suggests a role in O2 homeostasis. Insect Biochemistry And Molecular Biology, 72, 20–30. https://doi.org/10.1016/j.ibmb.2016.03.004
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Almost all insects are equipped with a tracheal system, which appears to be sufficient for O2 supply even in phases of high metabolic activity. Therefore, with the exception of a few species dwelling in hypoxic habitats, specialized respiratory proteins had been considered unnecessary in insects. The recent discovery and apparently universal presence of intracellular hemoglobins in insects has remained functionally unexplained. The fruitfly Drosophila melanogaster harbors three different globin genes (referred to as glob1-3). Glob1 is
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Gleixner, E., Ripp, F., Gorr, T. A., Schuh, R., Wolf, C., Burmester, T., & Hankeln, T. (2016). Knockdown of Drosophila hemoglobin suggests a role in O2 homeostasis. Insect Biochemistry And Molecular Biology, 72, 20–30. https://doi.org/10.1016/j.ibmb.2016.03.004