Publication: Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients
Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients
Date
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Mitamura, Y., Schulz, D., Oro, S., Li, N., Kolm, I., Lang, C., Ziadlou, R., Tan, G., Bodenmiller, B., Steiger, P., Marzano, A., de Prost, N., Caudin, O., Levesque, M., Stoffel, C., Schmid-Grendelmeier, P., Maverakis, E., Akdis, C. A., & Brüggen, M.-C. (2022). Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients. Allergy, 77(2), 595–608. https://doi.org/10.1111/all.14983
Abstract
Abstract
Abstract
BACKGROUND
Coronavirus disease 2019 (COVID-19) has been associated with cutaneous findings, some being the result of drug hypersensitivity reactions such as maculopapular drug rashes (MDR). The aim of this study was to investigate whether COVID-19 is associated with the development of the MDR.
METHODS
Blood and skin samples from COVID-19 patients (based on a positive nasopharyngeal PCR) suffering from MDR (COVID-MDR), healthy controls, non-COVID-19-related patients with drug rash with eosinophilia and systemic symptoms (DRESS), and
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Creators (Authors)
- Mitamura, Yasutaka
- Schulz, Daniel
- Oro, Saskia
- Li, Nick
- Kolm, Isabel
- Lang, Claudia
- Ziadlou, Reihane
- Tan, Ge
- Bodenmiller, Bernd
- Steiger, Peter
- Marzano, Angelo
- de Prost, Nicolas
- Caudin, Olivier
- Levesque, Mitchell
- Stoffel, Corinne
- Schmid-Grendelmeier, Peter
- Maverakis, Emanual
- Akdis, Cezmi A
- Brüggen, Marie-Charlotte
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Citations
Mitamura, Y., Schulz, D., Oro, S., Li, N., Kolm, I., Lang, C., Ziadlou, R., Tan, G., Bodenmiller, B., Steiger, P., Marzano, A., de Prost, N., Caudin, O., Levesque, M., Stoffel, C., Schmid-Grendelmeier, P., Maverakis, E., Akdis, C. A., & Brüggen, M.-C. (2022). Cutaneous and systemic hyperinflammation drives maculopapular drug exanthema in severely ill COVID-19 patients. Allergy, 77(2), 595–608. https://doi.org/10.1111/all.14983
