Publication:

Human Plasma and Recombinant Hemopexins: Heme Binding Revisited

Date

Date

Date
2021
Journal Article
Published version

Citations

Citation copied

Karnaukhova, E., Owczarek, C., Schmidt, P., Schaer, D. J., & Buehler, P. W. (2021). Human Plasma and Recombinant Hemopexins: Heme Binding Revisited. International Journal of Molecular Sciences, 22(3), 1199. https://doi.org/10.3390/ijms22031199

Abstract

Abstract

Abstract

Plasma hemopexin (HPX) is the key antioxidant protein of the endogenous clearance pathway that limits the deleterious effects of heme released from hemoglobin and myoglobin (the term “heme” is used in this article to denote both the ferrous and ferric forms). During intra-vascular hemolysis, heme partitioning to protein and lipid increases as the plasma concentration of HPX declines. Therefore, the development of HPX as a replacement therapy during high heme stress could be a relevant intervention for hemolytic disorders. A logical ap

Additional indexing

Creators (Authors)

  • Karnaukhova, Elena
    affiliation.icon.alt
  • Owczarek, Catherine
    affiliation.icon.alt
  • Schmidt, Peter
    affiliation.icon.alt
  • Schaer, Dominik J
    affiliation.icon.alt
  • Buehler, Paul W
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
22

Number

Number

Number
3

Page range/Item number

Page range/Item number

Page range/Item number
1199

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Spectroscopy, Molecular Biology, Catalysis, General Medicine, Computer Science Applications

Language

Language

Language
English

Publication date

Publication date

Publication date
2021-01-26

Date available

Date available

Date available
2021-07-07

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1422-0067

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Karnaukhova, E., Owczarek, C., Schmidt, P., Schaer, D. J., & Buehler, P. W. (2021). Human Plasma and Recombinant Hemopexins: Heme Binding Revisited. International Journal of Molecular Sciences, 22(3), 1199. https://doi.org/10.3390/ijms22031199

Gold Open Access
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