Publication: A genetically encoded fluorescent probe for imaging of oxygenation gradients in living
A genetically encoded fluorescent probe for imaging of oxygenation gradients in living
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Lidsky, P. V., Lukyanov, K. A., Misra, T., Handke, B., Mishin, A. S., & Lehner, C. F. (2018). A genetically encoded fluorescent probe for imaging of oxygenation gradients in living. Development, 145(4), dev156257. https://doi.org/10.1242/dev.156257
Abstract
Abstract
Abstract
Oxygen concentrations vary between tissues of multicellular organisms and change under certain physiological or pathological conditions. Multiple methods have been developed for measuring oxygenation of biological samples and However, most require complex equipment, are laborious and have significant limitations. Here we report that oxygen concentration determines the choice between two maturation pathways of DsRed FT (Timer). At high oxygen levels, this DsRed derivate matures predominantly into a red fluorescent isoform. By contras
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Creators (Authors)
- Lidsky, Peter V
- Lukyanov, Konstantin A
- Misra, Tvisha
- Handke, Björn
- Mishin, Alexander S
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Citations
Lidsky, P. V., Lukyanov, K. A., Misra, T., Handke, B., Mishin, A. S., & Lehner, C. F. (2018). A genetically encoded fluorescent probe for imaging of oxygenation gradients in living. Development, 145(4), dev156257. https://doi.org/10.1242/dev.156257
