Publication: γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control
γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control
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Ruchti, F., Tuor, M., Mathew, L., McCarthy, N. E., & LeibundGut-Landmann, S. (2024). γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control. PLoS Pathogens, 20, e1011668. https://doi.org/10.1371/journal.ppat.1011668
Abstract
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Abstract
Stable microbial colonization of the skin depends on tight control by the host immune system. The lipid-dependent yeast Malassezia typically colonizes skin as a harmless commensal and is subject to host type 17 immunosurveillance, but this fungus has also been associated with diverse skin pathologies in both humans and animals. Using a murine model of Malassezia exposure, we show that Vγ4$^{+}$
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- Ruchti, Fiorella
- Tuor, Meret
- Mathew, Liya
- McCarthy, Neil E
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Citations
Ruchti, F., Tuor, M., Mathew, L., McCarthy, N. E., & LeibundGut-Landmann, S. (2024). γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control. PLoS Pathogens, 20, e1011668. https://doi.org/10.1371/journal.ppat.1011668
