Right Atrial Pressure During Exercise Predicts Survival in Patients With Pulmonary Hypertension

Lichtblau, Mona; Bader, Patrick R; Saxer, Stéphanie; Berlier, Charlotte; Schwarz, Esther I; Hasler, Elisabeth D; Furian, Michael; Grünig, Ekkehard; Bloch, Konrad E; Ulrich, Silvia

doi:10.1161/JAHA.120.018123

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Lichtblau, M., Bader, P. R., Saxer, S., Berlier, C., Schwarz, E. I., Hasler, E. D., Furian, M., Grünig, E., Bloch, K. E., & Ulrich, S. (2020). Right Atrial Pressure During Exercise Predicts Survival in Patients With Pulmonary Hypertension. Journal of the American Heart Association, 9(22), e018123. https://doi.org/10.1161/JAHA.120.018123

Abstract

Background We investigated changes in right atrial pressure (RAP) during exercise and their prognostic significance in patients assessed for pulmonary hypertension (PH). Methods and Results Consecutive right heart catheterization data, including RAP recorded during supine, stepwise cycle exercise in 270 patients evaluated for PH, were analyzed retrospectively and compared among groups of patients with PH (mean pulmonary artery pressure [mPAP] ≥25 mm Hg), exercise-induced PH (exPH; resting mPAP <25 mm Hg, exercise mPAP >30 mm Hg, and m