Publication: Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence
Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence
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Steeb, B., Claudi, B., Burton, N. A., Tienz, P., Schmidt, A., Farhan, H., Mazé, A., & Bumann, D. (2013). Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence. PLoS Pathogens, 9, e1003301. https://doi.org/10.1371/journal.ppat.1003301
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Pathogen access to host nutrients in infected tissues is fundamental for pathogen growth and virulence, disease progression, and infection control. However, our understanding of this crucial process is still rather limited because of experimental and conceptual challenges. Here, we used proteomics, microbial genetics, competitive infections, and computational approaches to obtain a comprehensive overview of Salmonella nutrition and growth in a mouse typhoid fever model. The data revealed that Salmonella accessed an unexpectedly divers
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Steeb, B., Claudi, B., Burton, N. A., Tienz, P., Schmidt, A., Farhan, H., Mazé, A., & Bumann, D. (2013). Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence. PLoS Pathogens, 9, e1003301. https://doi.org/10.1371/journal.ppat.1003301