Publication: Genetic risk factors predict disease progression in Crohn’s disease patients of the Swiss inflammatory bowel disease cohort
Genetic risk factors predict disease progression in Crohn’s disease patients of the Swiss inflammatory bowel disease cohort
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Ditrich, F. (2021). Genetic risk factors predict disease progression in Crohn’s disease patients of the Swiss inflammatory bowel disease cohort. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-217259
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Background:
Crohn’s disease (CD) may progress from an inflammatory to a stricturing or penetrating disease phenotype. The aim of our study was to identify single nucleotide polymorphisms (SNPs) that predict disease progression in patients of the Swiss IBD Cohort Study (SIBDCS). Methods:
We applied a multi-state Markov model for progression behavior of CD with three behavioral states according to the Montreal classification. The model considered transition from B1 to B2/B3 or from B2 to B3 stage. Model dynamics were summarized with t
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Ditrich, F. (2021). Genetic risk factors predict disease progression in Crohn’s disease patients of the Swiss inflammatory bowel disease cohort. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-217259
