Publication: Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus
Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus
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Albisetti, G. W., Ghanem, A., Foster, E., Conzelmann, K.-K., Zeilhofer, H. U., & Wildner, H. (2017). Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus. Journal of Neuroscience, 37(43), 10358–10371. https://doi.org/10.1523/JNEUROSCI.1277-17.2017
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Abstract
Glycoprotein-deleted (ΔG) rabies virus-mediated monosynaptic tracing has become a standard method for neuronal circuit mapping, and is applied to virtually all parts of the rodent nervous system including the spinal cord and primary sensory neurons. Here we identified two classes of unmyelinated sensory neurons (non-peptidergic/NP- and C-LTMR/TH neurons) that are resistant to direct and transsynaptic infection from the spinal cord with rabies viruses carrying glycoproteins in their envelopes that are routinely used for infection of CN
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- Albisetti, Gioele W
- Ghanem, Alexander
- Foster, Edmund
- Conzelmann, Karl-Klaus
- Wildner, Hendrik
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Albisetti, G. W., Ghanem, A., Foster, E., Conzelmann, K.-K., Zeilhofer, H. U., & Wildner, H. (2017). Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus. Journal of Neuroscience, 37(43), 10358–10371. https://doi.org/10.1523/JNEUROSCI.1277-17.2017
