Publication: Effect of N-acetylcysteine on acute allograft rejection after rat lung transplantation
Effect of N-acetylcysteine on acute allograft rejection after rat lung transplantation
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Erne, B. V., Jungraithmayr, W., Buschmann, J., Arni, S., Weder, W., & Inci, I. (2013). Effect of N-acetylcysteine on acute allograft rejection after rat lung transplantation. Annals of Thoracic Surgery, 95(3), 1021–1027. https://doi.org/10.1016/j.athoracsur.2012.11.008
Abstract
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Abstract
BACKGROUND: N-Acetylcysteine (NAC) attenuates ischemia-reperfusion injury after lung transplantation in animal models. The purpose of this study is to evaluate a protective effect of NAC against acute lung rejection. METHODS: Rat single-lung transplantation was performed in four groups (n = 7 per group). In NAC groups, donors and recipients received NAC 150 mg/kg per day intraperitoneally before transplantation and recipients thereafter until euthanasia. Control groups (CON) received 0.5 mL of 0.9% saline solution intraperitoneally in
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- Erne, Barbara V
- Jungraithmayr, Wolfgang
- Buschmann, Johanna
- Arni, Stephan
- Weder, Walter
- Inci, Ilhan
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Erne, B. V., Jungraithmayr, W., Buschmann, J., Arni, S., Weder, W., & Inci, I. (2013). Effect of N-acetylcysteine on acute allograft rejection after rat lung transplantation. Annals of Thoracic Surgery, 95(3), 1021–1027. https://doi.org/10.1016/j.athoracsur.2012.11.008