Publication: Beneficial effects of exosomes secreted by cardiac-derived progenitor cells and other cell types in myocardial ischemia
Beneficial effects of exosomes secreted by cardiac-derived progenitor cells and other cell types in myocardial ischemia
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Barile, L., Milano, G., & Vassalli, G. (2017). Beneficial effects of exosomes secreted by cardiac-derived progenitor cells and other cell types in myocardial ischemia. Stem Cell Investigation, 4, 93. https://doi.org/10.21037/sci.2017.11.06
Abstract
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Abstract
When injected into acutely infarcted rodent or pig hearts, naturally secreted nanovesicles known as exosomes from cardiac-derived progenitor cells (CPCs) reduce scar size and improve cardiac function. In this regard, exosomes fully mimic the benefits of injecting their parent cells. This recognition paves the way to the development of exosome-based, cell-free treatments for heart disease that could possibly supplant cell-based therapies. Mechanisms of benefit of these vesicles are incompletely understood but cytoprotection, stimulatio
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- Barile, Lucio
- Milano, Giuseppina
- Vassalli, Giuseppe
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Barile, L., Milano, G., & Vassalli, G. (2017). Beneficial effects of exosomes secreted by cardiac-derived progenitor cells and other cell types in myocardial ischemia. Stem Cell Investigation, 4, 93. https://doi.org/10.21037/sci.2017.11.06
