Symptoms of depression and anxiety are independently associated with clinical recurrence of inflammatory bowel disease

Mikocka-Walus, Antonina; Pittet, Valerie; Rossel, Jean-Benoît; von Känel, Roland; Swiss IBD Cohort Study Group

doi:10.1016/j.cgh.2015.12.045

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Mikocka-Walus, A., Pittet, V., Rossel, J.-B., von Känel, R., & Swiss IBD Cohort Study Group. (2016). Symptoms of depression and anxiety are independently associated with clinical recurrence of inflammatory bowel disease. Clinical Gastroenterology and Hepatology, 14(6), 829–835. https://doi.org/10.1016/j.cgh.2015.12.045

Abstract

BACKGROUND & AIMS: We examined the relationship between symptoms of depression and anxiety and clinical recurrence of inflammatory bowel disease (IBD) in a large patient cohort. We considered the progression of depression and anxiety over time. METHODS: We collected clinical and treatment data on 2007 adult participants of the Swiss IBD study (56% with Crohn's disease [CD], 48% male) performed in Switzerland from 2006 through 2015. Depression and anxiety symptoms were quantified by using the Hospital Anxiety and Depression Scale. The